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Question
Biology
Posted 6 months ago
 Explain why 10%neutral buffered formalin is an ideal fixative?
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Answer from Sia
Posted 6 months ago
Answer
10% neutral buffered formalin is an ideal fixative because it preserves tissue morphology and prevents autolysis and putrefaction.
Solution
a
Preservation of tissue morphology: 10% neutral buffered formalin cross-links proteins, which stabilizes tissue architecture and prevents degradation
b
Prevention of autolysis and putrefaction: The fixative inhibits enzymatic breakdown and bacterial growth, which can otherwise compromise tissue integrity
Key Concept
Tissue fixation
Explanation
Fixation preserves tissue samples for histological examination by stabilizing their structure and preventing decay. 10% neutral buffered formalin is effective at achieving this while maintaining the tissue's morphological characteristics.

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