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Biology
Posted 7 months ago
Activation of a B cell that binds a T-dependent antigen requires
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Answer from Sia
Posted 7 months ago
Answer
Activation of a B cell that binds a T-dependent antigen requires interaction with helper T cells and the presence of cytokines.
Solution
a
Antigen recognition: The B cell receptor (BCR) on the B cell surface binds to a specific T-dependent antigen
b
Helper T cell engagement: The B cell processes the antigen and presents peptide fragments on its surface MHC class II molecules to helper T cells
c
Cytokine signaling: Helper T cells, upon recognizing the antigen-MHC complex, release cytokines that signal the B cell to proliferate and differentiate into plasma cells and memory B cells
Key Concept
B cell activation by T-dependent antigens requires assistance from helper T cells and cytokines.
Explanation
This process ensures that B cells are activated in a controlled manner, leading to a specific and effective immune response.

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