Assuming complete penetrance, what is the most likely mode of inheritance of this rare disease?

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∻Answer∻ ⚹ The most likely mode of inheritance of this rare disease, assuming complete penetrance, is autosomal recessive. ⚹ ∻Solution∻ ‖ a ⋮ Complete penetrance implies that individuals who inherit the disease allele(s) will express the disease phenotype. ‖ ‖ b ⋮ Rarity of the disease suggests that it is not common in the population, which is often the case with autosomal recessive diseases, as two copies of the rare allele are needed for the phenotype to be expressed. ‖ ‖ c ⋮ If the disease were autosomal dominant, it would likely be more common and observed in every generation, as only one copy of the allele would be necessary to express the disease. ‖ ‖ d ⋮ The probability of being a carrier for an autosomal recessive condition is higher than the probability of being affected, which explains the presence of carriers in the population and the rarity of the disease's expression. ‖ ∻Key Concept∻ ⚹ Autosomal recessive inheritance ⚹ ∻Explanation∻ ⚹ In autosomal recessive inheritance, a rare disease manifests in individuals who have two copies of a recessive allele, which is consistent with the disease's rarity and the assumption of complete penetrance. ⚹◊What is the significance of complete penetrance in the context of genetic inheritance of rare diseases in Biology?⍭ Generate me a similar question◊

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