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Question
Biology
Posted 7 months ago

Describe how antibacterial drugs inhibit/attack cell walls, membranes, protein synthesis, nucleic acid synthesis and give at least 2 examples
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Answer from Sia
Posted 7 months ago
Answer
Antibacterial drugs inhibit or attack bacterial cell walls, membranes, protein synthesis, and nucleic acid synthesis in various ways. Examples include Penicillin and Tetracycline.
Solution
a
Cell Wall Inhibition: Antibacterial drugs like Penicillin prevent the synthesis of peptidoglycan, which is crucial for bacterial cell wall integrity. Without a proper cell wall, bacteria cannot maintain their shape and are prone to lysis
b
Membrane Disruption: Drugs such as Polymyxins interact with the bacterial cell membrane, leading to increased permeability and cell death
c
Protein Synthesis Inhibition: Antibiotics like Tetracycline bind to the bacterial ribosome, blocking the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, which inhibits protein synthesis
d
Nucleic Acid Synthesis Inhibition: Drugs such as Fluoroquinolones inhibit enzymes like DNA gyrase, which are essential for DNA replication and transcription in bacteria, leading to the inhibition of nucleic acid synthesis
Key Concept
Antibacterial drugs target essential processes in bacteria, such as cell wall synthesis, membrane integrity, protein synthesis, and nucleic acid synthesis, to exert their effects.
Explanation
These drugs are designed to exploit the differences between bacterial cells and human cells, allowing them to selectively target and kill bacteria while minimizing harm to the host.

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