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Question
Biology
Posted 4 months ago
Describe the antiviral activity of acyclovir, AZT, and protease inhibitors.
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Answer from Sia
Posted 4 months ago
Answer
Acyclovir, AZT, and protease inhibitors interfere with different stages of viral replication.
Solution
a
Acyclovir: Targets herpes viruses by mimicking nucleosides and getting incorporated into viral DNA
b
AZT (Zidovudine): Targets HIV by inhibiting the reverse transcriptase enzyme, preventing viral RNA from being converted into DNA
c
Protease inhibitors: Block the HIV protease enzyme, preventing the maturation of new viruses
Key Concept
Antiviral drugs target specific stages of the viral life cycle to inhibit replication.
Explanation
Acyclovir resembles the nucleoside guanine, AZT inhibits reverse transcription, and protease inhibitors prevent the assembly of functional viral proteins.

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