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siad's Question
Posted 2 months ago
Great explaination!
Highlights similarities and differences of the cell entry mechanisms of HIV and SARS - CoV-2
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Answer from Sia
Posted 2 months ago
The cell entry mechanisms of HIV and SARS-CoV-2 have both similarities and differences.
Similarity: Both HIV and SARS-CoV-2 use receptor-mediated endocytosis to enter host cells
Difference: HIV primarily targets CD4+ T cells using the CD4 receptor and co-receptors CCR5 or CXCR4, while SARS-CoV-2 targets epithelial cells using the ACE2 receptor
Similarity: Both viruses undergo membrane fusion to release their genetic material into the host cell
Key Concept
Receptor-mediated endocytosis
Both HIV and SARS-CoV-2 utilize specific receptors on the host cell surface to gain entry, but they target different receptors and cell types.

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