Jack and Jill are both deaf, their parents are all hearing abled, All of Jack and Jill's children are deaf, including Peter. Peter is married to Wendy who is also deat, and her parents are also hearing abled. Peter and Wendy have two children, both of them are hearing abled. Explain the most likely mode of inheritance of deafness, in this case, given the available information.

Jack en Jill is albei doof, en hul ouers horend. Al die kinders van Jack en Jill is doof, insluitend Peter. Peter is getroud met Wendy, wat ook doof is, maar haar overs kan ook hoor. Peter en Wendy het twee kinders, albei is horend. Verduidelik die mees waarskynlike wyse van oorerwing van doofheid. in die geval, gegewe die beskikbare inligting.

Question

Jack and Jill are both deaf, their parents are all hearing abled, All of Jack and Jill's children are deaf, including Peter. Peter is married to Wendy who is also deat, and her parents are also hearing abled. Peter and Wendy have two children, both of them are hearing abled. Explain the most likely mode of inheritance of deafness, in this case, given the available information.

Jack en Jill is albei doof, en hul ouers horend. Al die kinders van Jack en Jill is doof, insluitend Peter. Peter is getroud met Wendy, wat ook doof is, maar haar overs kan ook hoor. Peter en Wendy het twee kinders, albei is horend. Verduidelik die mees waarskynlike wyse van oorerwing van doofheid. in die geval, gegewe die beskikbare inligting.

Accepted Answer

∻Answer∻ ⚹ The most likely mode of inheritance of deafness in this family is autosomal recessive. ⚹ ∻Solution∻ ‖ a ⋮ Autosomal Recessive Inheritance: This mode of inheritance requires two copies of the mutant gene to express the trait. ‖ ‖ b ⋮ Parental Generation: Since all parents are hearing and all of their children are deaf, the parents are likely carriers of the recessive deafness allele. ‖ ‖ c ⋮ F1 Generation: Jack and Jill, as well as Peter and Wendy, are deaf, indicating they have both recessive alleles. ‖ ‖ d ⋮ F2 Generation: Peter and Wendy's children are hearing, which suggests they inherited one normal allele from each parent, making them carriers. ‖ ∻Key Concept∻ ⚹ Autosomal Recessive Inheritance ⚹ ∻Explanation∻ ⚹ In autosomal recessive inheritance, two copies of a recessive allele are necessary for the individual to express the trait. Carriers have one copy of the recessive allele but do not express the trait. When two carriers have children, there is a 25% chance for each child to be affected, a 50% chance to be a carrier, and a 25% chance to be unaffected and not a carrier. In this family, the pattern suggests that deafness is caused by a recessive allele, with the deaf individuals being homozygous recessive and the hearing individuals who are parents or children of deaf individuals being carriers (heterozygous). ⚹◊What is the most likely mode of inheritance for deafness in this family, based on the information provided?⍭ Generate me a similar question◊

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