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Chemistry
Posted 4 months ago

Make appropriate synthesis designs to synthesize the carboxylic acid anhydrides given below, starting from the compounds you want and using the reagents that may be necessary.
a)benzoic acetic anhydride
b)succinic anhydride
c)butanoic anhydride
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Answer from Sia
Posted 4 months ago
Solution
1
Identify the starting materials and reagents: To synthesize carboxylic acid anhydrides, we need to start with the corresponding carboxylic acids and use reagents that facilitate the formation of anhydrides
2
Synthesize benzoic acetic anhydride: - Start with benzoic acid and acetic acid. - Use a dehydrating agent like acetic anhydride or phosphorus pentoxide (P2O5P_2O_5) to remove water and form the anhydride. - The reaction can be represented as: C6H5COOH+CH3COOHundefinedP2O5C6H5COOCOCH3+H2O \text{C}_6\text{H}_5\text{COOH} + \text{CH}_3\text{COOH} \xrightarrow{\text{P}_2\text{O}_5} \text{C}_6\text{H}_5\text{COOCOCH}_3 + \text{H}_2\text{O}
3
Synthesize succinic anhydride: - Start with succinic acid. - Use a dehydrating agent like acetic anhydride or phosphorus pentoxide (P2O5P_2O_5) to remove water and form the anhydride. - The reaction can be represented as: HOOC-(CH2)2COOHundefinedP2O5(CH2)2COOCO+H2O \text{HOOC-(CH}_2\text{)}_2\text{COOH} \xrightarrow{\text{P}_2\text{O}_5} \text{(CH}_2\text{)}_2\text{COOCO} + \text{H}_2\text{O}
4
Synthesize butanoic anhydride: - Start with butanoic acid. - Use a dehydrating agent like acetic anhydride or phosphorus pentoxide (P2O5P_2O_5) to remove water and form the anhydride. - The reaction can be represented as: 2CH3CH2CH2COOHundefinedP2O5CH3CH2CH2COOCOCH2CH3+H2O 2\text{CH}_3\text{CH}_2\text{CH}_2\text{COOH} \xrightarrow{\text{P}_2\text{O}_5} \text{CH}_3\text{CH}_2\text{CH}_2\text{COOCOCH}_2\text{CH}_3 + \text{H}_2\text{O}
Answer
The synthesis of carboxylic acid anhydrides involves starting with the corresponding carboxylic acids and using a dehydrating agent to remove water and form the anhydride.
Key Concept
Dehydration of carboxylic acids to form anhydrides
Explanation
Carboxylic acid anhydrides can be synthesized by dehydrating carboxylic acids using reagents like acetic anhydride or phosphorus pentoxide (P2O5P_2O_5). This process removes water and forms the anhydride.

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