What allows the RNA polymerase holoenzyme to recognize the promoter and bind to it, but is not found in the core polymerase in E. coli?

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∻Answer∻ ⚹ The RNA polymerase holoenzyme recognizes the promoter and binds to it due to the presence of the sigma factor, which is not found in the core polymerase. ⚹ ∻Solution∻ ‖ a ⋮ Sigma factor: The sigma factor is a protein that associates with the core RNA polymerase to form the holoenzyme. ‖ ‖ b ⋮ Promoter recognition: The sigma factor is responsible for recognizing the specific promoter sequences in the DNA, allowing the holoenzyme to bind specifically to promoters. ‖ ∻Key Concept∻ ⚹ Sigma factor in RNA polymerase holoenzyme ⚹ ∻Explanation∻ ⚹ The sigma factor is crucial for the initiation of transcription in E. coli as it enables the RNA polymerase holoenzyme to recognize and bind to promoter sequences. ⚹◊How does the sigma factor aid in the recognition of the promoter by the RNA polymerase holoenzyme in E. coli?⍭ Generate me a similar question◊

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