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Biology
Posted about 1 year ago
What is caretaker genes and gatekeeper genes
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Answer from Sia
Posted about 1 year ago
Answer
Caretaker genes and gatekeeper genes are types of tumor suppressor genes that play crucial roles in maintaining genomic stability and regulating cell growth.
Solution
a
Caretaker genes: These genes are responsible for maintaining the integrity of the genome by repairing DNA damage. They help prevent mutations that could lead to cancer. Examples include BRCA1 and BRCA2, which are involved in DNA repair mechanisms
b
Gatekeeper genes: These genes directly regulate cell growth and apoptosis (programmed cell death). They act as "gatekeepers" by controlling cell proliferation and eliminating damaged cells. Examples include TP53, which encodes the p53 protein, a crucial regulator of the cell cycle and apoptosis
Key Concept
Tumor suppressor genes
Explanation
Caretaker genes maintain genomic stability by repairing DNA, while gatekeeper genes regulate cell growth and apoptosis to prevent cancer.
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