Asksia AI LOGO

Sia

Question
Biology
Posted 3 months ago
the link between cholera and diarrhea with membrane biology in mind
Sign in to unlock the answer
Answer from Sia
Posted 3 months ago
Answer
Cholera causes diarrhea through the disruption of ion transport in the intestinal membrane.
Solution
a
Cholera toxin (CT) : The bacterium Vibrio cholerae produces CT, which binds to the intestinal epithelial cells
b
cAMP levels : CT activates adenylate cyclase, causing an increase in intracellular cAMP
c
Ion transport disruption : Elevated cAMP stimulates the secretion of Cl⁻ ions into the intestinal lumen and inhibits Na⁺ absorption
d
Water efflux : The osmotic gradient created by Cl⁻ secretion draws water into the lumen, causing diarrhea
Key Concept
Cholera toxin's effect on ion transport
Explanation
Cholera toxin leads to increased cAMP in intestinal cells, disrupting ion transport and causing water to flow into the intestinal lumen, resulting in diarrhea.

Not the question you are looking for? Ask here!

Enter question by text

Enter question by image

Upgrade to Asksia Pro

Join a AskSia's Pro Plan, and get 24/7 AI tutoring for your reviews, assignments, quizzes and exam preps.

Unlimited chat query usages
Strong algorithms that better know you
Early access to new release features
Study Other Question