the link between cholera and diarrhea with membrane biology in mind

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∻Answer∻ ⚹ Cholera causes diarrhea through the disruption of ion transport in the intestinal membrane. ⚹ ∻Solution∻ ‖ a ⋮ Cholera toxin (CT) ⋮ The bacterium Vibrio cholerae produces CT, which binds to the intestinal epithelial cells. ‖ ‖ b ⋮ cAMP levels ⋮ CT activates adenylate cyclase, causing an increase in intracellular cAMP. ‖ ‖ c ⋮ Ion transport disruption ⋮ Elevated cAMP stimulates the secretion of Cl⁻ ions into the intestinal lumen and inhibits Na⁺ absorption. ‖ ‖ d ⋮ Water efflux ⋮ The osmotic gradient created by Cl⁻ secretion draws water into the lumen, causing diarrhea. ‖ ∻Key Concept∻ ⚹ Cholera toxin's effect on ion transport ⚹ ∻Explanation∻ ⚹ Cholera toxin leads to increased cAMP in intestinal cells, disrupting ion transport and causing water to flow into the intestinal lumen, resulting in diarrhea. ⚹◊How does the cholera toxin affect the ion channels in the cell membranes leading to diarrhea?⍭ Generate me a similar question◊

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