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Question
Biology
Posted 7 months ago

why can only Fe2+\mathrm{Fe} 2+ bind oxygen in heme and not Fe3+\mathrm{Fe} 3+
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Answer from Sia
Posted 7 months ago
Answer
Only Fe2+Fe^{2+} can bind oxygen in heme, not Fe3+Fe^{3+}
Solution
a
Iron oxidation states: Iron can exist in multiple oxidation states, but in the context of heme, the relevant states are Fe2+Fe^{2+} (ferrous) and Fe3+Fe^{3+} (ferric)
b
Oxygen binding: The heme group in hemoglobin binds oxygen through its iron atom. Only Fe2+Fe^{2+} can reversibly bind oxygen
c
Electron configuration: Fe2+Fe^{2+} has the appropriate electron configuration to form a stable complex with oxygen, whereas Fe3+Fe^{3+} does not
Key Concept
Iron oxidation states in heme
Explanation
Fe2+Fe^{2+} can bind oxygen due to its electron configuration, while Fe3+Fe^{3+} cannot form a stable complex with oxygen.

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