Which type of mutation would MOST likely disrupt the activity of an enzyme, making it nonfunctional?
A A mutation that changes an amino acid located away from the active site
(B) A mutation that changes an amino acid located in the active site.
(C) A mutation that changes an amino acid located in a binding spot for an inhibitor.
(D) A mutation that does not cause the structure of the enzyme to change.

Question

Accepted Answer

***B*** ∻Key Concept∻ ⚹Active Site Mutation⚹ ∻Explanation∻ ⚹A mutation that changes an amino acid located in the active site of an enzyme is most likely to disrupt its activity, making it nonfunctional. The active site is crucial for the enzyme's catalytic function, and any alteration here can significantly affect the enzyme's ability to bind to its substrate and catalyze reactions.⚹◊What is the significance of amino acid location in relation to enzyme function and activity?⍭ Generate me a similar question◊

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