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Question
Biology
Posted 6 months ago
what happens to the expression of these genes when trypotphan levels are high versus low? why?
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Answer from Sia
Posted 6 months ago
Answer
Gene expression is repressed when tryptophan levels are high and activated when tryptophan levels are low.
Solution
a
High tryptophan levels : When tryptophan levels are high, tryptophan acts as a corepressor and binds to the repressor protein. This complex then binds to the operator region of the operon, preventing RNA polymerase from transcribing the genes involved in tryptophan synthesis
b
Low tryptophan levels : When tryptophan levels are low, the repressor protein is inactive and cannot bind to the operator. This allows RNA polymerase to bind to the promoter and transcribe the genes necessary for the synthesis of tryptophan
Key Concept
Gene regulation in response to tryptophan levels
Explanation
This is an example of negative feedback regulation where the end product, tryptophan, regulates its own synthesis by inhibiting gene expression when present in sufficient quantities.

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